Roche Holding AG (SWX:ROG) signed an agreement to acquire Tensha Therapeutics, Inc. from HealthCare Ventures LLC and others for approximately $540 million on January 10, 2016. The consideration includes an upfront cash payment of $115 million, plus additional contingent payments of up to $420 million based on the achievement of certain predetermined clinical and regulatory milestones. As of July 13, 2016, HealthCare sold its stake in Tensha to Roche.

The transaction is subject to customary closing conditions and anticipated to close in the first quarter of 2016.