Wall Street is set to open lower on Friday morning, as traders look set to continue taking profits on Nvidia and the major technology stocks following the "rally" of recent weeks, which has led to record-breaking indexes.

Half an hour before the opening, futures on the main New York indices were down between 0.1% and 0.2%, heralding a note of weakness at the opening.

The S&P 500 and Nasdaq had already ended in the red last night, dragged down by profit-taking on the "tech" giants, virtually all of which had hit new highs recently.

A victim of sector rotation in favor of the more defensive Dow Jones stocks, the Nasdaq lost 0.8% on Thursday, but the composite index is still up 18% year-to-date.

Among the American tech heavyweights, it's Nvidia's sudden downward turn that's raising the most questions.

After opening up 3.5%, the AI chipmaker plunged into the red to end down 3.5%.

For investors, the question is whether the stock represents a buying opportunity at current levels", points out Rania Gule, market analyst at XS.com.

Another example of profit-taking, Apple retreated by more than 2% after having surged by 22% in three months and having recently reached all-time highs.

However, this downturn may look like a normal technical retreat, especially as major economic news will be lacking today, giving investors the opportunity to continue their profit-taking.

Traders are awaiting the release, early in the session, of the S&P Global PMI index, which should show that the US economy remains buoyant, particularly in the services sector.

On the bond front, the yield on 10-year Treasuries continues to fall, returning to levels close to the highest since the end of March, at nearly 4.22%.

The session could be marked by a degree of volatility on this day of the "four witches", marked by the expiry of numerous index and equity options and futures contracts.

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