Item 5.02 Departure of Directors or Certain Officers; Election of Directors;

Appointment of Certain Officers; Compensatory Arrangements of Certain

Officers.

On December 31, 2019, Eran Nadav, Ph.D. resigned from his position as a member of the Board of Directors of Trevi Therapeutics, Inc., a Delaware corporation (the "Company"). Dr. Nadav's resignation was not due to any disagreement with the Company on any matter relating to the Company's operations, policies or practices.

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