TheraVet : Inside Information / Other news releases

TheraVet announces the commercial launch of a local and

sustained antibiotic releasing bone substitute

BIOCERA-VETCOMBO-CLEAN, a unique bone substitute for antibiotic delivery:

1. combinable with all main antibiotics covering the usual germs involved in

bone infections,

1. providing sustained antibiotic delivery for up to 30 days above MIC1 and, o unique osteo-conductive & osteo-integrative properties

First successful case already reported

Gosselies (Wallonia, Belgium), May 31, 2023 - 7.30 am CEST - TheraVet (ISIN:

BE0974387194 - ticker: ALVET), a pioneering company in the management of osteoarticular

diseases in pets, announces the commercial launch of BIOCERA-VET® Combo-Clean, a new reference for BIOCERA-VET, its comprehensive bone substitutes range, in Europe and

United Kingdom. BIOCERA-VET® Combo-Clean will be available on our website (www.bioceravet.com).

Infections can be a major concern when it comes to orthopedic surgeries and can occur in 5% of these surgeries. In order to prevent damage to the bone, a treatment with antibiotics and removal of infected implants and materials is generally recommended. Also, preventive treatment can occur for high-risk surgeries (e.g., open fracture from a trauma or bite).

BIOCERA-VET® Combo-Clean is the solution to bring locally high concentration of antibiotics and to ensure stability thanks to its mechanical strength. To manage bone infections, it can be mixed with the 7 most commonly used antibiotics (covering all the most common germs involved in bone infection). In addition to its properties as bone substitute (i.e., mechanical strength, osteointegration and osteoconduction), and superior ergonomics (i.e., easy-to-prepare, highly injectable), BIOCERA-VET® Combo-Clean features optimal antibiotic release profile enabling a local but also long-lasting antimicrobial action for up to 30 days.

The combination of all these properties makes of BIOCERA-VET® Combo-Clean the first-of-its- kind sustained antibiotic releasing bone substitute.

1 MIC: Minimum Inhibitory Concentration is the lowest concentration of an antibacterial agent which, under strictly controlled in vitro conditions, completely prevents visible growth of the test strain of an organism

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About TheraVet SA

TheraVet is a veterinary biotechnology company specializing in osteoarticular treatments for companion animals. The Company develops targeted, safe and effective treatments to improve the quality of life of pets suffering from joint and bone diseases. For pet owners, the health of their pets is a major concern and TheraVet's mission is to address the need for innovative and curative treatments. TheraVet works closely with international opinion leaders in order to provide a more effective response to ever-growing needs in the field of veterinary medicine. TheraVet is listed on Euronext Growth® Paris and Brussels, has its head office in Belgium (Gosselies) with a US subsidiary.

For more information, visit the TheraVet websiteor follow us on LinkedIn/ Facebook/ Twitter

About BIOCERA-VET

In close collaboration with an international scientific board, THERAVET® has developed a new line of calcium-phosphate and biological bone substitutes, BIOCERA-VET®.BIOCERA-VET® is a full range of innovative, easy-to-use, efficient & cost-effective bone substitutes indicated in bone surgeries where a bone graft is required and as a palliative alternative in the management of canine osteosarcoma. Based on extremely promising clinical results, this line offers the possibility of a better, more convenient and more efficient orthopedic surgery.

BIOCERA-VET® is declined in different lines:

• BIOCERA-VET® BONE SURGERY RTU, a ready-to-use highly injectable self-hardening calcium- phosphate cement
• BIOCERA-VET® SMARTGRAFT, a naturally osteoconductive bone graft
• BIOCERA-VET® GRANULES, an affordable biocompatible calcium-phosphate bone substitute
• BIOCERA-VET® OSTEOSARCOMA RTU, a ready-to-use highly injectable calcium-phosphate bone substitute for cementoplasty
• BIOCERA-VET® COMBO-CLEAN, a local and long-lasting antibiotic delivery calcium-phosphate bone substitute

For more information, visit BIOCERA-VETwebsite.

Contacts
TheraVet	NewCap	NewCap Belgique
Chief Operating Officer	Investor Relations and	Press Relations
Sabrina Ena	Financial Communications	Laure-Eve Monfort
[e-mail]	Théo Martin / Nicolas Fossiez	[e-mail]
Tel: [phone]	[e-mail]	Tel: + 32 (0) 489 57 76 52
	Tel: [phone]
Chief Corporate Officer
Julie Winand	Press Relations
[e-mail]	Arthur Rouillé
	[e-mail]
	Tel: [phone]

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