QSAM Biosciences Inc. announced the opening of enrollment into the 2nd grouping of participants (Cohort 2) after completing Cohort 1 in February in its Phase 1 study evaluating CycloSam® in the treatment of bone cancer. QSAM's study is a multiple-center, open label, dose escalation clinical trial intended to determine the maximum tolerated dose of CycloSam® in patients, and also assess early safety and efficacy signals. The total dosage of the active radioisotope Samarium-153 to be received by participants in the second cohort is 50% higher than the total dose received by participants in the first cohort.

Adults with bone cancer that has migrated or metastasized from the breast, lung or prostate is common and frequently fatal. QSAM is dedicated to developing its Cyclosam® product for this important patient population, and patients with any of these bone cancer types are eligible for this clinical trial. Osteosarcoma, while still a rare pediatric disease, is the most common form of bone cancer in children and young adults (ages 15-39) with primary high-grade bone malignancy; and Ewing's Sarcoma bone cancer is the second most common form of bone cancer in children.