Item 8.01 Other Events.


Explanatory Note: In this report, Predictive Oncology Inc. (the "Company") is
disclosing certain information regarding its reportable segments and its
executive compensation for the year ended December 31, 2020. These disclosures
are intended to satisfy the disclosure requirements for certain registration
statements into which this report is or will be incorporated by reference.

Information Regarding Reportable Segments





In Note 10 to the Condensed Consolidated Financial Statements in its Form 10-Q
for the period ended September 30, 2020 (the "September 2020 10-Q"), the Company
reported a change in its reportable segments as of the third quarter of 2020, as
determined in accordance with ASC 280 - Segment Reporting. Factors used to
determine the Company's reportable segments include the availability of separate
financial statements, the existence of locally based leadership across
geographic regions, the economic factors affecting each segment, and the
evaluation of reportable results at the segment level. The Chief Operating
Decision Maker ("CODM") allocates the Company's resources for each of the
reportable segments and evaluates their relative performance. Each reportable
segment listed below has separate financial statements and locally based
leadership that are evaluated based on the results of their respective
segments. It should be noted that the reportable segments below have different
products and services. The financial information is consolidated and evaluated
regularly by the CODM in assessing performance and allocating resources.



During the third quarter of 2020, the Company considered, whether under ASC
280-10-50-3 there was a change in its reportable segments. As a result of the
formation of the new Soluble subsidiary, the Company believes the Soluble
business represents an reportable segment. Soluble signed its first contract
during the third quarter of 2020. The Company also believes it is appropriate to
combine our Skyline Medical and Skyline Europe entities into a single reportable
segment based on the changes to our physical presence and intent to sign future
contracts through the US entity. Finally, the Company believes the Helomics
business continues to be an reportable segment. As of the third quarter of 2020,
the Company has three reportable segments: Skyline, Helomics and Soluble.



In the September 2020 10-Q, the Company reported segment information for the
three and nine month periods ended September 30, 2020 and 2019. In this report,
the Company is reporting certain segment information for the years ended
December 31, 2019 and 2018. The reported financial information below has been
reclassified to conform to the current presentation. This information is
intended to assist investors in making comparisons of the Company's historical
financial information with future financial information.



The table below summarizes the reclassified presentation of the Company's segment reporting for years ended December 31, 2019 and 2018.





                                                                       Year Ended December 31, 2019
                                      Skyline          Helomics          Soluble         Corporate           Total
Revenue                            $  1,363,118     $      48,447     $          -     $          -     $   1,411,565
Depreciation and Amortization           (48,420 )        (556,538 )              -          (99,925 )        (704,883 )
Impairment expense                            -        (8,100,000 )              -         (770,250 )      (8,870,250 )

Loss on equity method investment              -                 -          

     -         (439,637 )        (439,637 )
Segment Loss                       $ (3,125,290 )   $ (12,354,108 )   $          -     $ (3,901,368 )   $ (19,390,766 )




                                       2





                                           December 31, 2019
           Skyline        Helomics       Soluble     Corporate        Total
Assets   $ 969,793     $ 21,275,306     $     -     $ 130,411     $ 22,375,510




In 2018, substantially all the Company revenues and expenses were located or
derived from operations in the United States and recorded under the Skyline
segment.



                                          December 31, 2018
           Skyline      Helomics      Soluble      Corporate         Total
Assets   $ 973,744     $     -       $     -     $ 2,735,555     $ 3,708,999

The table below summarizes the Company's segment reporting as originally reported on the Annual Report on Form 10-K for the year ended December 31, 2019.

Year Ended December 31, 2019


                                      Domestic       International        Helomics         Corporate           Total
Revenue                            $  1,275,048     $       88,070     $      48,447                -     $   1,411,565
Depreciation and Amortization           (43,728 )           (4,692 )        (556,538 )        (99,925 )        (704,883 )
Impairment expense                            -                  -        (8,100,000 )       (770,250 )      (8,870,250 )
Loss on equity method investment              -                  -                 -         (439,637 )        (439,637 )
Segment Loss                       $ (2,783,531 )   $     (351,759 )   $ 

(12,354,108 ) $ (3,901,368 ) $ (19,390,766 )






                                              December 31, 2019
          Domestic      International        Helomics       Corporate        Total
Assets   $ 670,841     $      298,952     $ 21,275,306     $ 130,411     $ 22,375,510




In 2018, substantially all the Company revenues and expenses were located or
derived from operations in the United States and recorded under the domestic
segment.



                                             December 31, 2018
            Domestic     International    Helomics         Corporate           Total
Assets   $ 932,367     $      41,377           -       $ 2,735,255     $ 3,708,999
















                                       3





Executive Compensation



Overview



This section describes the material elements of the compensation awarded to,
earned by or paid to our Chief Executive Officer and our Chief Financial
Officer, collectively referred to as the "Named Executive Officers." We did not
have any other executive officers, as determined in accordance with SEC rules,
during 2020.


Summary Compensation Table for Fiscal 2020 and 2019

The following table provides information regarding the compensation earned during the fiscal years ended December 31, 2020 and December 31, 2019 by each of the Named Executive Officers:





       Nameand                                                       (1)           (1)
      Principal                                                     Stock        Option         All Other            Total
       Position             Year        Salary         Bonus        Awards       Awards        Compensation      Compensation


Carl Schwartz, CEO (2)       2020     $ 430,000     $       -     $ 46,002     $       -     $         -        $     476,002
                             2019     $ 100,000     $       -     $      -     $ 376,600     $         -        $     476,600

Bob Myers, CFO (3)           2020     $ 327,838     $       -     $ 15,334     $       -     $         -        $     343,172
                             2019     $ 270,833     $       -     $      -     $ 100,597     $         -        $     371,430

(1) Represents the actual compensation cost granted during 2020 and 2019 as

determined pursuant to FASB ASC 718 - Stock Compensation.

(2) Dr. Schwartz received a salary increase to $460,000 annually on September

23, 2020 retroactively effective to July 1, 2020. Dr. Schwartz opted to take

nine months of his 2019-year salary as stock options in lieu of cash. Dr.

Schwartz received options to purchase 47,702 shares of common stock in lieu

of a cash salary in 2019. The shares all vest at the time of grant and range

in price from $1.54 per share to $7.90 per share for 2019 grants. Dr.

Schwartz received 300,000 restricted stock units on September 23, 2020,

payable in shares of common stock and vesting in equal annual installments

over three years.

(3) Mr. Myers received a salary increase to $345,000 annually on September 23,

2020 retroactively effective to July 1, 2020. Mr. Myers received a salary

increase on August 1, 2019 to an annualized amount of $300,000. Mr. Myers

received $19,250 paid in 2019 for 2018 accrued bonus. Mr. Myers received

options to purchase 16,600 shares of common stock vesting over two (2) years

in eight (8) equal installments priced at $1.54 per share. Mr. Myers

received 100,000 restricted stock units on September 23, 2020, payable in


      shares of common stock and vesting in equal annual installments over three
      years.




















                                       4




Outstanding Equity Awards at Fiscal Year-end for Fiscal 2020

The following table sets forth certain information regarding outstanding equity awards held by the named executive officers as of December 31, 2020:





                                                 Option Awards                                 Stock Awards(1)
                                                                                                          Equity
                                                                                                         Incentive
                                                                                            Equity         Plan
                                                                                           Incentive      Awards:
                                                                                             Plan        Market or
                                                                                            Awards:       Payout
                                                                                           Number of     Value of
                                                                                           Unearned      Unearned
                                                                                            Shares,       Shares,
                                           Number of                                       Units or      Units or
                                           Securities                                        Other         Other
                                           Underlying       Option          Option        Rights That   Rights That
                                          Options (#)      Exercise      

Expiration Have Not Have Not


                          Grant Date      Exercisable      Price ($)          Date        Vested (#)    Vested ($)
Carl Schwartz              7/19/2013                7     $     1.54        7/19/2023
                           6/30/2015               26     $     1.54        6/30/2025
                           6/30/2015               26     $   775.00        6/30/2025
                           3/31/2016               59     $    42.50        3/31/2026
                           6/30/2016              133     $    37.50        6/30/2026
                           9/30/2016              121     $    41.25        9/30/2026
                          12/31/2016              179     $     1.54       12/31/2026
                          12/31/2016              714     $    28.00       12/31/2026
                           3/31/2017              238     $    21.00        3/31/2027
                           6/22/2017           37,689     $     1.54        6/22/2027
                          11/10/2017            2,834     $     1.54       11/10/2027
                            1/2/2018           14,175     $     1.54         1/2/2028
                           6/30/2018           12,168     $     1.54        6/30/2028
                            8/1/2018            4,490     $     1.54         8/1/2028
                            1/2/2019           32,305     $     1.54         1/2/2029
                            4/4/2019           20,000     $     1.54         4/4/2029
                            7/1/2019            4,219     $     7.90         7/1/2029
                            8/1/2019            5,128     $     6.50         8/1/2029
                            9/1/2019            6,050     $     5.51         9/1/2029
                           3/31/2020            3,174     $     1.58        3/31/2030
                           6/30/2020            3,049     $     1.64        6/30/2030
                           9/30/2020            6,142     $     0.81        9/30/2030
                          12/31/2020           20,481     $     0.73       12/31/2030       300,000     $ 300,000

Bob Myers                  8/13/2012               53     $     1.54        8/13/2022
                           3/18/2013               42     $     1.54        3/18/2023
                            3/6/2014               14     $     1.54         3/6/2024
                           9/16/2016              357     $     1.54        9/16/2026
                           6/22/2017           30,411     $     1.54        6/22/2027
                            4/4/2019           16,600     $     1.54         4/4/2029       100,000     $ 100,000

(1) Represents restricted stock units (RSUs) granted in 2020. The market value


      is based on the closing sale price of the Company's common stock of $1.00 at
      January 15, 2021.
















                                       5




Executive Compensation Components for Fiscal 2020





Base Salary. Base salary is an important element of our executive compensation
program as it provides executives with a fixed, regular, non-contingent earnings
stream to support annual living and other expenses. As a component of total
compensation, we generally set base salaries at levels believed to attract and
retain an experienced management team that will successfully grow our business
and create stockholder value. We also utilize base salaries to reward individual
performance and contributions to our overall business objectives but seek to do
so in a manner that does not detract from the executives' incentive to realize
additional compensation through our stock options.
. . .


Item 9.01 Financial Statements and Exhibits.





(d)    Exhibits.



Exhibit
Number  Description

  4.1     Form of Placement Agent Warrant issued to H.C. Wainwright & Co., LLC
        or its designees in connection with certain financing transactions in
        2020 and 2021.






















                            (Signature page follows)













                                       11

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