Item 2.02 Results of Operations and Financial Condition.

Otonomy, Inc. reports that its estimated cash balance including cash and cash equivalents totaled $40.1 million as of September 30, 2022.

The information provided in this Item 2.02 of this Form 8-K shall not be deemed "filed" for purposes of Section 18 of the Securities Exchange Act of 1934, as amended (the "Exchange Act"), or otherwise subject to the liabilities of that section, nor shall it be deemed incorporated by reference into any of Otonomy's filings under the Securities Act of 1933, as amended, or the Exchange Act, except as expressly set forth by specific reference in such filing.

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