Neuronetics, Inc. announced a new peer-reviewed publication in the Journal of Clinical Psychiatry, presenting real-world evidence of the efficacy of NeuroStar Advanced Therapy for adult patients who suffer concurrently from anxiety symptoms and major depressive disorder, also known as anxious depression. Using data from the world's largest depression outcomes registry of more than 15,000 patients, the publication authors analyzed a sample of over 1,800 patients. These 1,800 patients were treated with NeuroStar TMS in commercial clinics and represented a diversity of patients with MDD and moderate-to-severe anxiety symptoms. Patients with anxious depression exhibited clinically meaningful anxiety symptom improvement and antidepressant effects.

These results represent large treatment effect sizes of 1.47 on the GAD-7 and 1.74 on the PHQ-9 after receiving NeuroStar TMS treatment. The findings of this study also showed that the magnitude of improvement in depressive symptoms did not differ based on baseline patient anxiety severity, with all groups experiencing robust and nearly equivalent antidepressant effects.