Item 7.01 Regulation FD Disclosure

On January 9, 2023, MainStreet Bancshares, Inc. (the "Company") announced that it will conduct a virtual webcast and quarterly earnings conference call on Monday, January 23, 2023, at 2:00 p.m. Eastern Time during which the Company will discuss fourth quarter and year ended results as well as provide an update on recent activities. Investors that are interested in attending the virtual webcast should contact Hattie Lester by email at hlester@mstreetbank.com or by phone at (571)-375-1364.

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