Item 5.02. Departure of Directors or Certain Officers; Election of Directors; Appointment of Certain Officers; Compensatory Arrangements of Certain Officers.

On January 6, 2020, John Sculley retired from the Board of Directors (the "Board") of Kaleido Bioscience, Inc. (the "Company"), and all committees thereof, as part of an effort to reduce his company board commitments. Mr. Sculley's departure is not the result of any disagreement with the Company on any matter relating to the Company's operations, policies or practices.

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