Inspira Technologies OXY B.H.N. Ltd. announced the receipt of the Israeli Ministry of Health's medical devices and accessories ("AMAR") approval for the INSPIRA ART100, an Extra-Corporeal Membrane Oxygenation and Cardiopulmonary Bypass system. This is a pivotal milestone in Inspira's strategy to conduct business development activities to bring its innovative products and technologies to the market. The Company believes that receiving Israeli regulatory approval marks an important step towards growing local support and adoption for the INSPIRA??

ART100 and demonstrates Inspira's capabilities in obtaining regulatory approvals for its products. The INSPIRA? ART (Gen 2), also known as the INSPIRA?

ART500, will include the Company's Adaptive Blood Oxygenation technology and is being designed to continuously measure the patient's blood parameters in real-time, delivering needed oxygen volume straight into the blood. By elevating patient oxygen saturation levels in minutes, this technology potentially allows patients to remain awake during treatment and therefore may enable patients to be treated in and beyond intensive care units, reducing the need for mechanical ventilation systems that require intubation and medically induced coma. The Company's INSPIRA?

ART100 system received FDA 510(k) clearance for Cardiopulmonary Bypass procedures and AMAR certification for Extra-Corporeal Membrane Oxygenation and Cardiopulmonary Bypass procedures. The Company's other products, including the INSPIRA? ART (Gen 2) and HYLA?

blood sensor, have not yet been tested or used in humans and have not been approved by any regulatory entity.