Notice to the Market - Business Combination between GNDI and Hapvida: Presentation of Potential Synergies Related to the Business Combination

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NOTRE DAME INTERMÉDICA	HAPVIDA PARTICIPAÇÕES E
PARTICIPAÇÕES S.A.	INVESTIMENTOS S.A.
CNPJ 19.853.511/0001-84	CNPJ 05.197.443/0001-38
Publicly-held company	Publicly-held company

NOTICE TO THE MARKET

PRESENTATION OF POTENTIAL SYNERGIES RELATED TO THE BUSINESS

COMBINATION

Notre Dame Intermédica Participações S.A. (B3: GNDI3) (GNDI) and Hapvida

Participações e Investimentos S.A. (B3: HAPV3) (Hapvida and, together with GNDI, the Companies), in compliance with current regulations, inform their shareholders and to the market in general, in addition to the Material Fact disclosed on January 20, 2022, that the Companies will make a webcast presentation (in Portuguese, with simultaneous translation into English) for shareholders, analysts, investors and the market in general on the potential synergies related to the business combination between GNDI and Hapvida.

Date: February 7, 2022, Monday, at 10:00 am (Brasilia time), 8:00 am (New York time), with an expected duration of 1 hour.

Webcast: access the Investor Relations (IR) website of the Companies at the addresses ri.gndi.com.br and ri.hapvida.com.br, where the access links will be available.

Presenters: From GNDI, Irlau Machado, CEO, Marcelo Moreira, CFO and Glauco Desiderio, Investor Relations Director, will be present. From Hapvida will be present, Jorge Pinheiro, CEO, Maurício Teixeira, CFO, and Guilherme Nahuz, Head of Investor Relations and ESG.

Format: Prepared remarks followed by a question-and-answer session.

The webcast presentation will be available at the Companies' IR website about 30 minutes before, or during the webcast.

São Paulo, SP, January, 31, 2022	Fortaleza, CE, January, 31, 2022
Glauco Desiderio	Mauricio Teixeira
Investors Relations Officer	CFO and Investor Relations Officer

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