Item 2.02Results of Operations and Financial Condition.

On January 25, 2022, First Busey Corporation ("First Busey") issued a press release disclosing financial results for the quarter ended December 31, 2021. A copy of the press release is attached hereto as Exhibit 99.1 and is incorporated herein by reference.

The information in Item 2.02 of this Current Report on Form 8-K and Exhibit 99.1 attached hereto is being "furnished" and will not, except to the extent required by applicable law or regulation, be deemed "filed" by First Busey for purposes of Section 18 of the Securities Exchange Act of 1934, as amended (the "Exchange Act"), or otherwise subject to the liabilities of that section, nor will any of such information or exhibits be deemed incorporated by reference into any filing under the Securities Act of 1933, as amended (the "Securities Act"), or the Exchange Act.

Item 7.01Regulation FD Disclosure.

On January 25, 2022, First Busey published supplemental slides discussing First Busey's financial results for the quarter ended December 31, 2021, and coronavirus disease 2019 response. A copy is attached hereto as Exhibit 99.2 and is incorporated herein by reference.

The information in Item 7.01 of this Current Report on Form 8-K and Exhibit 99.2 attached hereto is being "furnished" and will not, except to the extent required by applicable law or regulation, be deemed "filed" by First Busey for purposes of Section 18 of the Exchange Act, or otherwise subject to the liabilities of that section, nor will any of such information or exhibits be deemed incorporated by reference into any filing under the Securities Act or the Exchange Act.

Item 9.01Financial Statements and Exhibits.





(d)Exhibits.









Exhibit Number    Description of Exhibit
99.1                Press Release issued by First Busey Corporation, dated
                  January 25, 2022.

99.2                Supplemental slides issued by First Busey Corporation, dated
                  January 25, 2022.

104               Cover Page Interactive Data File (embedded within the Inline
                  XBRL document and included in Exhibit 101).

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