Eiger BioPharmaceuticals, Inc. announced the initiation of enrollment and first patient dosed in LOWR HDV – 4 (LOnafarnib With Ritonavir in Hepatitis Delta Virus – 4) at the Hannover Medical School in Hannover, Germany. LOWR HDV – 4 is an open label, dose titration study designed to evaluate the efficacy and tolerability of lonafarnib combined with ritonavir for a total of 24 weeks in fifteen patients with chronic hepatitis delta.