TR-1: NOTIFICATION OF MAJOR INTEREST IN SHARESi

1. Identity of the issuer or the underlying issuer of existing shares to which voting rights are attached: ii

Regenersis plc

2 Reason for the notification (please tick the appropriate box or boxes):

An acquisition or disposal of voting rights

Yes

An acquisition or disposal of qualifying financial instruments which may result in the acquisition of shares already issued to which voting rights are attached

No

An acquisition or disposal of instruments with similar economic effect to qualifying financial instruments

No

An event changing the breakdown of voting rights

No

Other (please specify):

N/A

3. Full name of person(s) subject to the notification obligation: iii

IMPAX ASSET MANAGEMENT LIMITED

4. Full name of shareholder(s)

(if different from 3.):iv

Impax Environmental Markets plc Impax Environmental Markets Ireland The Environment Agency Fund

5. Date of the transaction and date on

which the threshold is crossed or reached: v

23 December 2011

6. Date on which issuer notified:

30 December 2011

7. Threshold(s) that is/are crossed or reached: vi, vii

10%

8. Notified details:

A: Voting rights attached to shares viii, ix

Class/type of shares

if possible using the ISIN CODE

Situation previous to the triggering transaction

Resulting situation after the triggering transaction

Class/type of shares

if possible using the ISIN CODE

Number of Shares

Number of Voting Rights

Number of shares

Number of voting rights

% of voting rights x

Class/type of shares

if possible using the ISIN CODE

Number of Shares

Number of Voting Rights

Direct

xi

Direct

xii

Indirect

Direct

Indirect

GB00B06GNN57

4,495,514

10.0301%

4,455,514

N/A

4,455,514

N/A

9.9408%

B: Qualifying Financial Instruments

Resulting situation after the triggering transaction

Type of financial instrument

Expiration date xiii

Exercise/

Conversion Period xiv

Number of voting rights that may be acquired if the instrument is exercised/ converted.

% of voting rights

NIL

C: Financial Instruments with similar economic effect to Qualifying Financial Instruments

xv, xvi

Resulting situation after the triggering transaction

Type of financial instrument

Exercise price

Expiration date xvii

Exercise/ Conversion

period xviii

Number of voting rights instrument refers to

% of voting rights xix,

xx

NIL

Nominal

Delta

NIL

Total (A+B+C)

Number of voting rights

Percentage of voting rights

4,455,514

9.9408%

9. Chain of controlled undertakings through which the voting rights and/or the financial instruments are effectively held, if applicable: xxi

Impax Environmental Markets plc (2,713,479 shares 6.0541%) Impax Environmental Markets Ireland (1,292,035 shares 2.8827%) The Environment Agency Fund (450,000 shares 1.0040%)

Proxy Voting:

10. Name of the proxy holder:

N/A

11. Number of voting rights proxy holder will cease to hold:

N/A

12. Date on which proxy holder will cease to hold voting rights:

N/A

13. Additional information:

14. Contact name:

Michael Knight

Compliance Officer

15. Contact telephone number:

+44 (0) 20 7434 1122

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