Anika Therapeutics, Inc. announced that its Integrity Implant System is now in full market release and broadly available across the U.S. The Integrity System, comprised of a hyaluronic acid-based implant with bone and tendon fixation components and innovative single use arthroscopic delivery instruments, is designed to protect an injured tendon and promote healing in rotator cuff repair and other tendon procedures. The system has been in limited release since November 2023. Rotator cuff tears often fail to heal properly following surgical repair and have shown a high incidence of retearing.

Bench-top testing shows that Integrity provides nearly 50% higher tensile strength, over 3 times greater suture retention strength, and over 3 times more tear resistance when hydrated compared to the market-leading collagen implant.1 Additionally, in a head-to-head preclinical study also comparing Integrity to the market-leading collagen implant, new collagenous tissue infiltration forming a new network of tendon tissue had occurred within the resorbing Integrity structure at 26 weeks, resulting in Integrity demonstrating greater regenerative capacity and the repaired tendon being 3 times greater in thickness. The scaffold component of the Integrity system is a porous, knitted, flexible construct combining Anika?s proprietary Hyaff material, a solid form of HA that supports tissue regeneration and resorbs over time, reinforced with non-resorbable polyethylene terephthalate (PET). Integrity is inherently strong and can be confidently manipulated arthroscopically, which offers a truly unique and differentiated solution for surgeons to treat a variety of tendon repairs.

Integrity can be affixed using PEEK bone staples, resorbable PLGA soft tissue tendon tacks or suture fixation, as desired, at the site of the rotator cuff repair. The U.S. soft tissue augmentation market is currently over $190 million, of which $150 million is in rotator cuff repair and is estimated to grow at a nearly 7% CAGR2 over the next 5 years, representing one of the high opportunity spaces in orthopedics. The launch of the Integrity Implant System continues Anika?s focus on delivering new, differentiated solutions, with a specific focus on the intersection of regenerative solutions and sports medicine, particularly around rotator cuff repair.

The full market release of the Integrity Implant System coincides with presence at the 2024 AOSSM Annual Meeting in Denver, Colorado. Join team of experts at Booth #520, where Integrity will be prominently featured and discover how this innovation can enhance patient outcomes when treating rotator cuff tears and other tendon repairs.