Natan T. Shaked

Curon Medical, Inc. develops, manufactures and markets proprietary products for the treatment of gastrointestinal disorders. Its products consist of radiofrequency generators and single-use disposable devices. The company was founded on May 1, 1997 and is headquartered in Fremont, CA.

Data Sciences International, Inc. offers telemetry instrumentation and software and services in support of research. Its services include data services, surgical services, validation services and technical training. The firm’s products include implantable and external telemetry, software, signal conditioners, glucose monitoring, infusion pumps and inhalation/exposure systems. The company was founded by Brian P. Brockway in 1984 and is headquartered in St. Paul, MN.

Velocimed LLC develops, manufactures, and markets medical devices. The firm's products are used in cardiology and neurology applications. The company was founded in 2001 by Jay Schmelter, Michael Berman, and Dennis W. Wahr and is headquartered in Maple Grove, MN.

UltraShape, Inc. manufactures and markets non-invasive devices for the aesthetic medical field. The company was founded by Betsy S. Atkins and Glicksman Ami in 2000 and is headquartered in San Ramon, CA.

BeneChill, Inc. develops non-invasive cooling technology for cerebral ischemia treatment. The company was founded by Michael L. Berman and Denise Barbut in 2004 is headquartered in San Diego, CA.

InspireMD Ltd. is a medical device company, which engages in the development and commercialization of platform technology for the treatment of vascular and coronary disease. It offers MicroNet stent, a device designed to trap and seal thrombus and plaque against the vessel wall, preventing embolization. The company was founded in 2005 and is headquartered in Tel Aviv, Israel.

InterValve, Inc. operates as a medical device company which develops aortic valvuloplasty balloons for treatment of calcific aortic stenosis. Its V8 product is enhanced with leaflet hyperextension without increasing the risk of annulus over-distension. The firm also develops tools for the percutaneous and trans-apical aortic valve replacement procedure. The company was founded by Wes Pedersen, Mark Ungs, Robert S. Schwartz and Robert A. Van Tassel in 2008 and is headquartered in Plymouth, MN.

Rebiotix, Inc. develops and commercializes medical therapies. It offers human microbiome, clostridium difficile, inflammatory bowel disease or ulcerative colitis, hepatic encephalopathy, multi-drug resistant organism, and microbiota restoration therapies. The company was founded by Lee A. Jones, Michael Berman, and Erwin A. Kelen in 2011 and is headquartered in Roseville, MN.

RiverVest Venture Management LLC (RiverVest Venture Partners) is a venture capital firm founded in 2000 by Tom C. Melzer, Jay W. Schmelter, Mark J. Mendel and Andrew B. Craig III. The firm is headquartered in St. Louis, Missouri with additional offices in San Diego and Cleveland.

Cornell University is an educational institution that offers undergraduate and post graduate programs. It was founded in 1865 and is based in Ithaca, NY.

Tel-Aviv University operates as a university in Israel. Its faculties include arts, engineering, science, humanities, law, life science, management, medicine, and social science. The company was founded in 1956 and is headquartered in Ramat Aviv, Israel.

Bridgepoint Medical, Inc. develops interventional technology in the field of cardiology. It focuses on developing innovative and proprietary technology in the field of interventional cardiology for access to and treatment of chronic total occlusions. The company was founded by Michael L. Berman, Chad J Kugler and Robert E Atkinson in 2005 and is headquartered in Plymouth, MN.

Nicast Ltd. develops implantable medical devices from electrospun polymer nanofabrics for clinical applications. Its products include AVflo, a vascular access graft that provides for hemodialysis patients; and NovaMesh, a ventral hernia mesh, which offers resistance to tissue adhesion on the visceral-facing surface and promotes tissue ingrowth on the fascial surface. The company was founded by Alex Dubson in 1995 and is headquartered in Lod, Israel.

BrainsGate Ltd. develops medical devices. The firm specializes in therapies for patients suffering from central nervous system diseases. Its platform technology involves electrical stimulation of the Spheno-Palatine Ganglion, a nervous center known to increase cerebral blood flow. The company was founded by Yossi Gross and David Yarnitsky in 2000 and is headquartered in Caesarea, Israel.

Lutonix, Inc. develops and commercializes drug coated balloon catheters. Its catheters help to deliver therapeutic dose of paclitaxel. The firm’s catheters are used to treat peripheral and coronary lesions. The company was founded in July 2007 by Dennis Wahr and Lixiao Wang and is headquartered in New Hope, MN.

UltraShape redefines aesthetic medicine by developing, manufacturing and marketing innovative non-invasive technologies for fat cell destruction and body sculpting. The company develops and markets clinically proven safe and effective solutions that enhance the lives of patients. The UltraShape proprietary technology employs pulsed (non-thermal) focused ultrasound that instantly, selectively and permanently destroys fat cells without affecting surrounding structures. Founded in 2000, UltraShape has sold Contour I devices in more than 50 countries, demonstrating safety and efficacy. The UltraShape Contour I system, is authorized for marketing outside the U.S. It is the first clinically proven non-invasive solution that offers measurable lasting body sculpting results for men and women with no need for maintenance treatments. The UltraShape system has been shown to be safe and effective in a multi-center controlled trial and numerous other peer-reviewed published independent clinical studies. The device is designed to produce mechanical, non-thermal, acoustic effects which target and selectively destroy (breakdown) fat cells, leaving surrounding critical structures such as skin, blood vessels, nerves, and connective tissue intact. The latest Contour I V3 system uses Vertical Dynamic Focus™ (VDF) pulsed (non-thermal) focused ultrasound that instantly and permanently destroys fat cells providing patients a convenient noninvasive no-downtime solution to reduce localized fat deposits and body circumference. The UltraShape procedure is based on a natural fat clearance process where triglycerides and cell debris from the destroyed fat cells are processed by the body's natural physiological and metabolic pathways. These pathways are the same that handle fat during weight loss. Results from UltraShape's peer-reviewed published multi-center controlled clinical trial and other independent clinical studies show that the released triglycerides do not accumulate to a clinically significant extent in the blood or liver. Over 200,000 patient treatments have been performed worldwide with the Contour I showing high patient satisfaction while demonstrating safety and efficacy. The UltraShape procedure is guided by proprietary real-time tracking and guidance technology designed to deliver smooth, uniform body contouring results. The software guides the operator through a pres-determined treatment algorithm designed to minimize risk of contour irregularities, a common side effect of invasive and non-invasive procedures. The UltraShape procedure is performed during a convenient, 'walk-in, walk-out' session carried out in an office-based environment; it requires no anesthesia or sedation. After treatment, patients immediately resume their daily routines with no need for maintenance treatments. The UltraShape Contour I received the CE Mark in 2005 and a medical device license from Health Canada in 2007. The Contour I system is not available for sale in the U.S; the Contour Plus system is an investigational product limited by U.S. law to investigational use only.

Paindure Ltd. develops biodegradable formulation for slow release of local anesthetic in targeted nerve bundle. The company was founded on September 10, 2007 by Itschak Lamnsdorf and Alon Shalev and is headquartered in Herzliya, Israel.

ClearCut Medical Ltd. develops proprietary technology and tools for removal of cancer. Its product ClearSightTM MRI System, focuses on breast cancer lumpectomy for intraoperative margin assessment of surgically removed lumps. The firms applications include breast cancer biopsies, margin assessment of skin cancer, prostate cancer, colorectal cancer and lung cancer tissue microstructure. The company was founded by Eyal Kolka and Erez Golan in 2010 and is headquartered in Rehovot, Israel.

Pharmacentra LLC provides marketing and communications programs for the pharmaceutical and insurance industries. The private company is based in Norcross, GA. The CEO of the company is Dan Berman.

EndoSpan Ltd. develops novel endovascular system for endovascular aortic aneurysm repair. The firm is opening up options for repairing aneurysms and dissections in patients with anatomy previously unsuitable for endovascular therapy. The company was founded by Rafi Benary and Alon Shalev in 2009 and is headquartered in Herzlia, Israel.

SoniVie Ltd. engages in the development of a system for the treatment of pulmonary hypertension. Its products include Therapeutic Intra-Vascular Ultrasound (TIVUS) system, an intravascular, catheter-based technology that can cause denervation of nerves surrounding blood vessels and other structures like the bronchus. The company was founded by Moshe Arkin in 2014 and is headquartered in Rosh Haayin, Israel.

PulmOne Advanced Medical Devices Ltd. develops devices designed to allow lung function testing. It manufactures and distributes the MiniBox, an office based solution providing complete lung function testing in a portable device. The company was founded by Avi Lazar in 2006 and is headquartered in Raanana, Israel.

Part of Medtronic Plc, Mazor Robotics LLC is a company that specializes in the Mazor X Stealth Edition robotic guidance platform. The company is based in Orlando, FL. The platform is equipped with advanced software, robotic technologies, navigation, and instrumentation to support predictable surgical procedures. Christopher Prentice has been the CEO of the company since 2014.

unispectral Ltd. develops optical lens and image processing software for smart phones cameras. The firm serves the banking, pharmaceutical, agriculture, and automotive industry. The company was founded by Rami Feig, David Mendlovic, and Ariel Raz and is headquartered in Ramat Gan, Israel.

Owlytics Healthcare operates personalized physiology-tracking health detection platform. The company was founded by Gill Zaphrir and Yaron Recher in 2015 and is headquartered in Tel Aviv, Israel.

Trobix Innovation Ltd. engages in the development of therapies to remove the threat of antimicrobial resistance. Its products include ActiSense and GoTrap, technologies to reverse antibiotic resistance and remove antimicrobial resistant bacteria. The company was founded by Adi Elkeles and Nadav Kidron on March 27, 2018 and is headquartered in Tel Aviv, Israel.

CardiacSense Ltd. is a digital health company based in Caesarea, Israel. The Israeli company has developed a medical watch that integrates proprietary patent-protected sensors and software algorithms to provide continuous measurement of parameters such as core temperature, respiratory rate, blood pressure, oxygen saturation, and heart rate at CE and FDA-mandated accuracies. This provides an alternative to costly and complex invasive devices, addressing the increasing demand for remote patient monitoring and tele-health. The private company was founded in 2009 by Eldad Shemesh and Liat Shemesh, with Eldad Shemesh serving as the CEO since incorporation.