Dario Vignali

Millennium Pharmaceuticals, Inc. operates as a biopharmaceutical company. Its products include Ninlaro and Velcade. The company was founded in 1993 and is headquartered in Cambridge, MA.

Carnegie Mellon University is an American school that operates as a college or university. It is located in Pittsburgh, Pennsylvania.

Metabasis Therapeutics, Inc. engages in discovery, development and commercialization of novel drugs for metabolic diseases using the proprietary technology and the knowledge of processes and pathways within the liver that are useful for liver-selective drug targeting and treatment of metabolic diseases. Metabasis was incorporated in April 1997 and is headquartered in La Jolla, CA.

ALung Technologies, Inc. engages in the provision of respiratory support solutions. The company was founded by William Federspiel and Brack Hattler in 1997 and is headquartered in Pittsburgh, PA.

Idun Pharmaceuticals, Inc. is a biopharmaceutical company that engages in the discovery and development of human therapeutics to control apoptosis. The company was founded by John C. Reed, Robert H. Horvitz, and Lawrence C. Fritz in March 1993 and is headquartered in San Diego, CA.

IDEV Technologies, Inc. develops medical devices for endovascular uses. Its products include interventional cardiology, interventional radiology and vascular surgery. The company was founded by Sheldon J. Jeffery in 1999 and is headquartered in Webster, TX.

Alinea Pharmaceuticals, Inc. is a biopharmaceutical company focused on developing new therapeutics for the treatment of diabetes and metabolic disorders. The company was founded in August 2005 and is headquartered in Cambridge, MA.

Inspired Technologies, Inc. develops and supplies personal oxygen systems for patients. It provides personal oxygen portables based on SmartDose technology that continuously monitors the user’s breath rate and automatically adjusts the oxygen dose to the user’s activity level; and clinical oxygen dose recorders that enables to view patient response and conserver performance in real time. The firm also offers Viaspire SD Card Software, a software utility to upload and view patient data from SD Cards in SmartDose oxygen dosing units. The company was founded by Dan Easley in May 2005 and is headquartered in North Huntingdon, PA.

DNAtrix, Inc. operates as a biotech company which focuses on the development of oncolytic viruses for cancer. The firm’s offers DNX-2401 product which is an oncolytic virus designed specifically for treating Glioblastoma. It also works to expand its platform technology for treating other cancers, including ovarian, prostate and pancreatic cancer indications. The company was founded in 2005 by Francis Patrick McCormick, Alfred Yung, Charles Conrad, Cande Gomez-Manzano and Juan Fueyo and is headquartered in Houston, TX.

Metamark Genetics, Inc. provides molecular diagnostics services. It develops prognostic and predictive diagnostic tests that will enable personalized treatment planning for cancer patients. It transforms cancer diagnosis and treatment by developing pioneering diagnostic products based on its prognosis determinants platform. The company was founded by Kenneth E. Weg, Raju S. Kucherlapati, David Rimm, Lynda Chin and Ronald A. DePinho in November 2007 and is headquartered in Waltham, MA.

University of Pittsburgh Medical Center is a non-profit organization, which engages in the provision of hospital health programs and services. It operates through the following business units: Provider Services, Insurance Services, UPMC International, and UPMC Enterprises. It also develops programs in transplantation, cancer, neurosurgery, psychiatry, orthopedics, and sports medicine. The company was founded in 1893 and is headquartered in Pittsburgh, PA.

The Brigham & Women's Hospital, Inc. provides health care services. The firm offers treatment for cancer, cardio vascular, neurosciences, orthopedic, arthritis, women's health and clinical services. The company was founded in 1980 and is headquartered in Boston, MA.

Protez Pharmaceuticals, Inc. develops and manufactures pharmaceutical products. It develops antibiotics for infections & provides research service on intravenous & oral small molecule antibiotics to chronic and recurrent infections. The company was founded by Klaus Esser, Luigi Xerri & Christopher M. Cashman in 2003 and is headquartered in Malvern, PA.

TransForm Pharmaceuticals, Inc. develops and manufactures drugs. It integrates pharmaceutical sciences, materials science and high throughput experimentation by enabling novel technology. The company was founded by Nicholas Galakatos in 1999 and is headquartered in Lexington, MA.

Bay City Capital LLC (Bay City Capital) is a venture capital firm founded in 1997 by Fred Craves, John Diekman, and Thomas Pritzker. The firm is headquartered in California, United States.

Astellas Pharma US, Inc. manufactures pharmaceutical products. It offers cardiology, dermatology, immunology, infectious diseases, and urology. The firm was founded in 2005 and is headquartered in Northbrook, IL.

Astellas Venture Management LLC (Astellas Venture Management) is a venture capital subsidiary of Astellas Pharma Inc founded in 2000. The firm is headquartered in San Francisco, California.

The Sidney Kimmel Comprehensive Cancer Center offers immune-based treatments for cancer. The company was founded by Sidney Kimmel in 1973 and is headquartered in Baltimore, MD.

Avila Therapeutics, Inc. researches and develops covalent drugs. The company was founded in 2007 and is headquartered in Summit, NJ.

Wolfe Laboratories, Inc. operates as a contract research organization which provides integrated drug development solutions to the biopharmaceutical industry. It offers small molecule drug development, biologics development, and antibody-drug conjugates development services. The company was founded by Janet Wolfe in 1999 and is headquartered in Woburn, MA.

Part of Ono Pharmaceutical Co., Ltd., Ono Pharma USA, Inc. operates as a pharmaceutical platform. The company is based in Cambridge, MA. The company was founded in 1998. The CEO is Kunihiko Ito.

Mitobridge, Inc. operates as a biopharmaceutical company. It focuses on the development and discovery of products for mitochondrial function. The firm also offers treatments for genetic, metabolic, and neurodegenerative disorders as well as diseases and conditions of aging. The company was founded by Kazumi Shiosaki, Andrew Dillin, Ronald M. Evans, Johan Auwerx and Robert H. Horvitz in October 2011 and is headquartered in Cambridge, MA.

Tizona Therapeutics, Inc. is an immunology company harnessing the power of the immune system to develop treatments for cancer and autoimmune diseases. Its products include anti-ccr4 antibody for the treatment of cancer, il-35 antagonists for the treatment of cancer, and il-35 agonists for the treatment of autoimmune diseases. The company was founded by Charles G. Drake, Vijay K. Kuchroo, Drew M. Pardoll, Dario Vignali, Wayne A. Marasco and Jedd D. Wolchok and is headquartered in South San Francisco, CA.

UPMC Enterprises (UPMC Enterprises) is a venture capital subsidiary of University of Pittsburgh Medical Center founded in 2014. The firm is headquartered in Pittsburgh, Pennsylvania.

SparingVision SAS develops therapeutic approach for treatment of blinding inherited retinal diseases such as retinitis pigmentosa. The company was founded by Jose Alain Sahel, Thierry Leveillard and Florence Allouche Ghrenassia and is headquartered in Paris, France.

Globin Solutions, Inc. operates as a pre-clinical stage biopharmaceutical company. It researches and develops a rapidly acting antidote for carbon monoxide poisoning. The company was founded by Mark T. Gladwin, Jack D. Myers, Jason J. Rose and Jesus Tejero Bravo in 2017 and is headquartered in Pittsburgh, PA.

BlueSphere Bio, Inc. manufactures oncology drugs products. The company was founded by Mark Shlomchik, Warren Shlomchik, and Constantinos Panousis and is headquartered in Pittsburgh, PA.

Generian Pharmaceuticals, Inc. provides pharmaceutical services. The company is headquartered in Pittsburgh, PA.

Bicara Therapeutics, Inc. develops therapeutics. The company is based in Cambridge, MA. The CEO of the company is Claire Mazumdar.

Ono Venture Investment Inc (Ono Venture Investment) is a venture capital arm of Ono Pharmaceutical Co Ltd. founded in 2020. The firm is headquartered in San Francisco, California.

Larkspur Biosciences, Inc. is a company based in Watertown, MA that is pioneering a new wave in cancer therapy. Larkspur’s approach targets cancer-intrinsic factors that tumors use to escape immune detection and control to develop new treatment options for patients who cannot be helped by current therapies. The company is advancing first-in-class programs designed to eliminate tumor “bottlenecks” that drive immune evasion in colorectal cancer (CRC) and beyond. Larkx, the company’s proprietary bioinformatics platform, couples machine learning with tumor genetics to discover immune evasion pathways that originate in the tumor and enrich clinical strategies for potential responders to its therapies across multiple types of cancer. The company was founded by Nathanael S. Gray, Vijay Kumar Kuchroo, and Lewis Clayton Cantley. The CEO is Catherine Sabatos-Peyton.

Semma Therapeutics, Inc. develops transformative therapies for patients who currently depend on insulin injections. It focuses on combining proprietary cells with a state-of-the-art device to provide a true replacement for the missing beta cells in a diabetic patient without immunosuppression. The company was founded by Robert A. Millman, Walter A. Blättler, Felicia Pagliuca, Jeff Imbaro and Douglas A. Melton in 2015 and is headquartered in Cambridge, MA.