Danny B. Lange

Established in 2000, TransPharma Medical Ltd. is a specialty pharmaceutical company focused on the development and commercialization of drug-products utilizing an innovative active transversal drug delivery technology. Its current proprietary drug-product development programs include ViaDerm-hPTH (1-34), a transversal hPTH (1-34) product to treat osteoporosis, undergoing Phase 2B clinical trials, which is developed in collaboration with Eli Lilly, and two additional peptides currently in Phase 1. TransPharma's drug-product development activities utilize its well-proven RF-MicroChannel Technology. Its RF-MicroChannel technology enables the creation of an array of microscopic pores through the very outer skin surface, allowing the delivery of therapeutic doses of a wide portfolio of drugs, including biologics, Its main area of focus. TransPharma's implementation of the RF-MicroChannel Technology is the ViaDerm delivery system. Intended for home use, the ViaDerm delivery system consists of a reusable, handheld, low-cost device and a disposable patch containing a drug. TransPharma's goal is to develop multiple drug-products through strategic partnerships with leading pharmaceutical companies and through independent product development. They believe that combining partnered and proprietary product development ensures capitalizing of both the promise of its technology and its growing capabilities.

Maxillent Ltd. develops and manufactures dental implants. Its products include iraise, isure, prosthetics, surgical instruments and bone graft materials. The company was founded in 2008 and is headquartered in Herzliya, Israel.

Johnson & Johnson, Inc. provides insurance brokerage services. The company was founded in 1930 and is headquartered in Mount Pleasant, SC.

Discure Technologies manufactures medical equipment. The company is based in Herzliya, Israel. The Israeli company was founded by Yossi Gross. The CEO is Yuval Mandelbaum.

4Tech Cardio Ireland Ltd. develops and manufactures surgical devices. The company was founded in 2011 and is headquartered in Waltham, MA.

BetaStim Ltd. develops medical devices. The firm's implantable pulse generator is used to treat type II diabetes by applying electrical stimulation and monitoring gastrointestinal electrical activity. The company was founded by Yossi Gross and Jacob Ben Arie in 2006 and is headquartered in Caesarea, Israel.

G.I. View Ltd. develops endoscopy products for gastrointestinal applications. It offers edge endoscopes for the gastrointestinal market that set its products. The company was founded by Benad Goldwasser, Oz Cabiri and Yossi Gross in 2003 and is headquartered in Ramat Gan, Israel.

DuoCure Ltd. develops intraluminal minimally invasive implantable devices for the treatment of obesity. The company was founded by Elad Magal, Yossi Gross and Yael Karasik in 2005 and is headquartered in Tel Aviv, Israel.

GluSense Ltd. develops technology for Continuous Glucose Monitoring. The firm develops a miniature, Long-Term, Implantable Continuous Glucose Monitoring (CGM) system for diabetes patients, this system includes a miniature sensor implanted under the skin and an external wearable unit, e.g. a watch. Its wearable unit reads the signal from the implant and provides basic display and alarms. The company was founded by Yossi Gross in 2007 and is headquartered in Rehovot, Israel.

Valtech Cardio Ltd. develops devices for mitral valve repair and replacement. It specializes in the development of devices for mitral and tricuspid valve repair and replacement. The firm also offers full in-house development, manufacturing and clinical research capabilities, and patent applications. The company was founded by Amir Gross and Yossi Gross in March 2005 and is headquartered in Or Yehuda, Israel.

Vascular Dynamics, Inc. provides blood pressure modulation devices. It develops and commercializes a passive, catheter-delivered implant for the treatment of hypertension. The company was founded in 2008 and is headquartered in Mountain View, CA.

Nano Retina Ltd. develops artificial retina designed to restore sight. It also develops an implantable bionic chip, designed to return sight to those blinded by retinal degenerative diseases. The company was founded by Yossi Gross and James R. Von Her, II in 2009 and is headquartered in Herzliya, Israel.

Rainbow Medical Ltd. (Rainbow Medical) is a venture capital firm founded in 2007 by Efi Cohen Arazi and Yossi Gross. The firm is headquartered in HaMerkaz, Israel with an additional offices in China and United States.

Enopace Biomedical Ltd. develops medical devices to treat heart failure patients. The firm's technology consists of a minimally invasive, implantable neurostimulation device that increases cardiac efficiency by reducing left ventricular workload and improves the systolic/diastolic ratio. The company was by Yossi Gross and Amir Dagan in 2008 and is headquartered in Caesarea, Israel.

Beta-O2 Technologies Ltd. develops implantable bio-artificial pancreas devices. It offers BAir, a bio-artificial pancreas that provides a viable environment for islets of Langerhans to thrive and provide the body with insulin on demand. The company was founded by Pnina Vardi, Konstantin Bloch, and Yossi Gross in 2004 and is headquartered in Rosh-Haayin, Israel.

BrainsGate Ltd. develops medical devices. The firm specializes in therapies for patients suffering from central nervous system diseases. Its platform technology involves electrical stimulation of the Spheno-Palatine Ganglion, a nervous center known to increase cerebral blood flow. The company was founded by Yossi Gross and David Yarnitsky in 2000 and is headquartered in Caesarea, Israel.

EarlySense Ltd. provides patient monitoring systems. It offers continuous patient monitoring for heart rate, respiratory rate and motion, to potentially allow the clinical team to manage early detection of patient deterioration, fall prevention and pressure ulcers prevention. The firm develops system specifically for medical surgical, general care patients who are usually monitored by nurses once every four to six hours. The company was founded by Avner Halperin, Daniel H. Lange, Guy Shinar and Yossi Gross in 2004 and is headquartered in Ramat Gan, Israel.

Israel Aerospace Industries Ltd. engages in the development, sale, and maintenance of commercial and military aircrafts, missiles, and military electronic products. It operates through the following segments: Aviation, Military Aircraft, Missiles and Space Systems, and Elta Systems Ltd. The Aviation segment engages in the maintenance, renovation, and improvement of aircraft and aircraft engines, and conversion of passenger aircraft into cargo and refueling aircraft, and in the development and manufacture of aviation assemblies for military and commercial aircraft. The Military Aircraft segment engages in the development, manufacture, and sale of unmanned aircraft. The Missiles and Space Systems segment engages in the development, manufacture, and sale of attack and defense missile systems, satellites, and space assemblies. The Elta Systems Ltd segment engages in the military electronics field. The company was founded in 1953 and is headquartered in Lod, Israel.