May 2 (Reuters) - Canada's largest oil and gas producer Canadian Natural Resources missed Wall Street estimates for first-quarter profit on Thursday, hurt by lower production.

On an adjusted basis, the firm reported a profit of C$1.37 per share, below analysts' average estimate of C$1.48 per share, according to LSEG data. (Reporting by Kabir Dweit and Seher Dareen in Bengaluru; Editing by Varun H K)