Ascendis Pharma A/S announced that it has reached its target enrollment in the phase 3 heiGHt Trial of TransCon Growth Hormone for pediatric growth hormone deficiency (GHD). Given strong enthusiasm for the trial from investigators and subjects, as well as a commitment to those still in screening who may qualify, the company expects to randomize over 160 subjects. Based on one-year follow-up, top-line results are anticipated in the first quarter of 2019. The heiGHt Trial is a randomized, open-label, active-controlled phase 3 study evaluating treatment-naïve children with GHD who receive either once-weekly TransCon Growth Hormone (0.24 mg/kg/week) or daily Genotropin® (34 µg/kg/day or 0.24 mg/kg/week). The primary endpoint of the trial is annualized height velocity at 52 weeks. The primary statistical analysis will be a non-inferiority analysis comparing the two arms. Patients completing the heiGHt Trial may enroll in the enliGHten Trial, the company’s open-label long-term extension study. Ascendis Pharma is also conducting the fliGHt Trial to evaluate TransCon Growth Hormone in patients who have previously been treated with daily growth hormone therapy.