William Bushee

Medisyn Technologies, Inc. develops novel pharmaceuticals, nutraceuticals, and animal health products. The firm engages in the development of pre-qualified proprietary drug compounds. Its Forward Engineering platform is focused on predicting the behavior of molecules from topology. The company was founded in 1999 and is headquartered in Minnetonka, MN.

Bluestem Capital Co. LLC (Bluestem Capital) is a venture capital firm founded in 1989 by Steve T. Kirby. The firm is headquartered in Sioux Falls, South Dakota.

Sherpa Partners LLC (Sherpa Partners) is a venture capital firm founded in 1997 by Mac Lewis. The firm is headquartered in Edina, Minnesota.

California Institute of Technology provides education focusing on science, engineering, academia, business, and public service. The company was founded in 1891 and it is headquartered in Pasadena, CA.

eGistics, Inc. provides a scalable data archival solution for the financial services and healthcare industries. The company was founded by Bryan A. Bruton in 1994 and is headquartered in Plano, TX.

JMS Precision, Inc. manufactures and supplies precision equipment parts. It provides plastic, zinc and chrome coated materials. The company was founded in 1977 and is headquartered in Watertown, SD.

Pelstar LLC manufactures weighing scales. Its products include physician and primary care, acute care and hospital, long term care, stand-on, wheelchair, chair, bariatric, neonatal and pediatric, professional home care scales. It distributes the brand Health o meter® Professional. The company was founded in 1919 and is headquartered in McCook, IL.

Western Surety Co. provides surety and fidelity bond insurance products. The company is headquartered in Sioux Falls, SD.

SpringCM, Inc. provides an enterprise-class document management and workflow solution designed for online collaboration. Its cloud platform manages contracts and all types of documents across desktop, mobile, and partner applications like Salesforce. The company was founded by Christine Mason, Greg T. Buchholz, and Jeffrey Piper in 2005 and is headquartered in Chicago, IL.

Equinox Ophthalmic, Inc. operates as a biotechnology company. It specializes in cataract, corneal and glaucoma surgery. The company was founded by John Berdahl and is headquartered in Sioux Falls, SD.

Virtual Incision Corp. engages in the development of miniaturized surgical robots. It offers MIRA (miniaturized in vivo robotic assistant) surgical robotic platform. The company was founded by Shane M. Farritor and Dmitry Oleynikov in 2006 and is headquartered in Lincoln, NE.

Valley Queen Cheese Factory, Inc. produces dairy products. It offers chees, whey, anhydrous milk fat, and milk products. The company was founded by Alfred Nef and Alfred Gonzenbach in 1929 and is headquartered in Milbank, SD.

Kirby Capital Corp. provides alternative investment management services. The company is headquartered in Sioux Falls, SD.

Virun, Inc. develops effective drug delivery and food and beverage ingredients. Its products include OmegaH2O and Coenzyme Clear. The firm operates through three segments: food and beverage ingredient manufacturing, consumer product development and pharmaceutical drug delivery. The foods and beverage ingredient manufacturing segment produces novel food and beverage concentrates stemming from a patented portfolio. The consumer product development segment develops novel and patented consumer products that allow substantiated health claims. The pharmaceutical drug delivery segment utilizes its patented technologies to improve the pharmacokinetics (delivery) and dynamics (efficacy) of peptides and compounds that have poor oral bioavailability or over-all functionality. The company was founded in 2003 by Philip James Bromley and is headquartered in Walnut, CA.

Zeal provides business development services. It offers incubation, co-working and meeting space, interactive programs and services, peer networking, and mentorship. The company was founded in 2004 and is headquartered in Sioux Falls, SD.

OcuDoc, Inc. provides digital health services for eye care technologies. It develops TESA (The Eye Scan App) that helps vision diagnostics for licensed eye care providers. The company was founded in 2013 and is headquartered in Columbus, OH.

Noteswift, Inc. engages in the development of health information technology solutions. It offers Samantha, an electronic health record (HER) real time transcriptionist, which enables providers to dictate the narrative of a patient encounter and parse the text into usable and valued structured data for patient outcomes. The company was founded by Chris Russell in 2008 and is headquartered in Scottsdale, AZ.

TearClear Corp. operates as an early-stage medical science company. It develops a hydrogel filter to remove potentially harmful preservatives from multi dose topical ophthalmic products used to treat chronic diseases such as glaucoma, dry-eye and allergic conjunctivitis. The company was founded by Anuj Chauhan in 2015 and is headquartered in Copley, OH.

Sydnexis, Inc. engages in the production of ophthalmic pharmaceutical products. The company was founded by Gregory Isaac Ostrow in 2014 and is headquartered in San Diego, CA.

Tear Film Innovations, Inc. engages in the research and development of products for the treatment of evaporative dry eye and related syndromes. It offers iLux system, a handheld treatment device which enables eye care professionals to identify and treat blocked meibomian glands. The company was founded by Kabir Gambhir and Brian Kelleher in 2014 and is headquartered in San Diergo, CA.

Polycera, Inc. operates as a polymeric material platform. It offers a range of ultrafiltration performance beyond conventional ceramic and polymeric membranes. The company was founded by Eric Hoek and is headquartered in Los Angeles, CA.

Synq3 Restaurant Solutions LLC provides call center solutions for the restaurant industry. Its solutions include drive improvements, enhanced guest relationships, increased average check, improved guest experience and innovative technologies that reduce costs. The company was founded by Steve Bigari in January 2008 and is headquartered in Colorado Springs, CO.

TherOptix, Inc. develops and manufactures drug-eluting contact lens. The company is headquartered in San Francisco, CA.

Startup Sioux Falls provides business development services. The company was founded by Matt Paulson and is headquartered in Sioux Falls, SD.

Prismatic Software, Inc. is a company that provides an embedded integration platform for B2B software companies. The company is based in Sioux Falls, SD. The company's platform allows businesses to build and deploy integrations, integrate with their customer's apps, and add an integration marketplace to their SaaS product. Prismatic offers API connectors and other components to empower non-devs to build integrations for B2B SaaS customers with a low-code designer. Michael Zuercher has been the CEO of the company since 2019.

Neurolens, Inc. is a company that commercializes breakthrough technology to improve vision care. The company's patented contoured prism technology provides visual comfort for the nearly 65% of US adults who complain of headaches, neck/shoulder pain, and eyestrain when using digital devices, reading, or doing detail work. The company is based in Coppell, TX. Inspired by a breakthrough discovery linking optometry and neurology, Neurolens is unlocking a new dimension of vision care. The Neurolens contoured prism design helps the eyes work together comfortably, bringing the eyes into alignment to relieve painful symptoms. The technology is only available to independent eye care providers. The company was founded in 2012 by Davis Corley, and Pierre Bertrand has been the CEO of the company since 2019.

Homegrown Capital (Homegrown Capital) is a venture capital firm founded in 2021. The firm is headquartered in Brookings, South Dakota.

Colabra, Inc. provides software to optimize research workflows and data integration. The company is based in Claymont, DE. The company was founded by Leonard Paul Gollobin.